Influence of Nanoparticle Size and Shape on Oligomer Formation of an Amyloidogenic Peptide
نویسندگان
چکیده
منابع مشابه
Influence of Nanoparticle Size and Shape on Oligomer Formation of an Amyloidogenic Peptide.
Understanding the influence of macromolecular crowding and nanoparticles on the formation of in-register β-sheets, the primary structural component of amyloid fibrils, is a first step towards describing in vivo protein aggregation and interactions between synthetic materials and proteins. Using all atom molecular simulations in implicit solvent we illustrate the effects of nanoparticle size, sh...
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ژورنال
عنوان ژورنال: The Journal of Physical Chemistry Letters
سال: 2011
ISSN: 1948-7185
DOI: 10.1021/jz200330k